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Varieties of Hyphenated Gas Chromatography with Mass Spectrometry



Thomas J. Bruno


Because of the very powerful and common application of mass spectrometry with gas chromatography, the various technologies warrant more detailed consideration.[1-4] The following table provides basic information on the capabilities and applicability of the most common approaches. Clearly, the use of the single quadrupole is by far the most prevalent and economical method, but the other techniques are important and advantageous. We exclude methods that are typically not interfaced with gas chromatographic separations and that are highly specific in research settings (such as ion cyclotron mass spectrometry, and combined quadrupoles beyond the triple quad, and the various hybrid sector-quad-time of flight-ion trap combinations) that are used in fundamental ion chemistry research. We also exclude magnetic sector instruments that are seldom used with chromatography
CRC Handbook of Chemistry and Physics - 95th Edition
Publisher Info
Taylor and Francis, Boca, FL


gas chromatography mass spectrometry, quadrupole, time of flight


Bruno, T. (2014), Varieties of Hyphenated Gas Chromatography with Mass Spectrometry, Taylor and Francis, Boca, FL (Accessed April 14, 2024)
Created June 4, 2014, Updated February 19, 2017