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Toxicity Data for Fire Hazard Analysis



Richard G. Gann, Vyto Babrauskas, E Braun, Barbara C. Levin, M Paabo, Richard H. Harris Jr., Richard D. Peacock, S Yusa


A comprehansive methodology has been developed for obtaining and using smoke toxicity data for fire hazard analysis. The methodology comprises: determination that the post-flashover fire is the propert focus of smoke inhalation deaths; criteria for a useful bench-scale toxic potency (LC50) measurement method; a method which meets these criteria, especially validation against real-scale fires; a computational procedure for correcting the results for the CO levels observed in real-scale post-flashover fires; procedures for reducing the usage of animals and broadening the applicability of data by interpreting gas measurement data using the N-Gas Model; and a procedure for identifying whether a product produces smoke within the ordinary range of toxic potency for post-flashover fires. The method is currently being developed for standardization by the National Fire Protection Association and the American Society for Testing and Materials.
Proceedings Title
U.S./Japan Government Cooperative Program on Natural Resources (UJNR)
Conference Dates
October 27-November 2, 1992
Conference Location
Conference Title
Fire Research and Safety. 12th Joint Panel Meeting


fire safety, fire research, hazard analysis, fire hazard, toxicity, LC 50, animals, rats


Gann, R. , Babrauskas, V. , Braun, E. , Levin, B. , Paabo, M. , Harris, R. , Peacock, R. and Yusa, S. (1992), Toxicity Data for Fire Hazard Analysis, U.S./Japan Government Cooperative Program on Natural Resources (UJNR), Tsukuba, , [online], (Accessed July 24, 2024)


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Created October 27, 1992, Updated February 19, 2017