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Tissue Engineered Scaffolds for Screening Nanoparticle - Cell Interactions

Published

Author(s)

Kavita M. Jeerage, Elisabeth Mansfield, Tammy L. Oreskovic, Nikki S. Rentz, Timothy P. Quinn

Abstract

Long-term studies of nanoparticle-cell interactions require an advanced tissue-like environment in which nanoparticles are encapsulated with a population of cells for real-time and end-point analysis. By using soft tissue-mimicking hydrogels, the cells are provided with an environment that promotes normal cell function during prolonged nanoparticle exposure. PC12 cells in Collagen I and PEG 4600 hydrogels are considered here, with quantum dots as the model nanoparticle.
Proceedings Title
Proceedings of the 2010 Annual Meeting and Exposition of the Society for Biomaterials
Conference Dates
April 21-24, 2010
Conference Location
Seattle, WA
Conference Title
2010 Annual Meeting and Exposition of the Society for Biomaterials

Citation

Jeerage, K. , Mansfield, E. , Oreskovic, T. , Rentz, N. and Quinn, T. (2010), Tissue Engineered Scaffolds for Screening Nanoparticle - Cell Interactions, Proceedings of the 2010 Annual Meeting and Exposition of the Society for Biomaterials, Seattle, WA, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=904330 (Accessed July 23, 2024)

Issues

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Created April 21, 2010, Updated February 19, 2017