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Threading and Unthreading of Pseudorotaxanes of PEG/Acyclodextrin



Barry J. Bauer, Da-Wei Liu


The threading and unthreading kinetics of alpha-cyclodextrin onto polyethylene glycol is measured by small angle neutron scattering and gel permeation chromatography. The threading is autocatalytic, once threading of a PEG chain is started, it rapidly becomes fully threaded. Fully threaded chains associate, forming a separate phase. Upon heating, dilution, or addition of a good solvent the dethreading is extremely rapid, giving complete dethreading. Since the alpha-cyclodextrin molecule fits closely around a PEG molecule, stearic reasons alone cannot account for slow dethreading of pseutorotaxanes, and other effects such as strong ring-chain interactions must be present.
Polymer Preprints


cyclodextrine, GPC, kinetics, PEG, rotaxane, SANS


Bauer, B. and Liu, D. (2008), Threading and Unthreading of Pseudorotaxanes of PEG/Acyclodextrin, Polymer Preprints (Accessed June 20, 2024)


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Created October 16, 2008