Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Synthesis and Characterization of Poly(ethylene glycol) Dimethacrylate Hydrogels

Published

Author(s)

Sheng Lin-Gibson, S Bencherif, Joseph M. Antonucci, Horkay F. JonesRL

Abstract

Facile synthesis and detailed characterization of photo-polymerizable and biocompatible poly(ethylene glycol) dimethacrylates (PEGDM) and their hydrogels are described. Combined analyses of 1H NMR and MALDI-TOF MS confirmed the formation of prepolymers of high purity and narrow mass distribution (PD < 1.02). A systematic investigation into the structure and mechanical properties of PEGDM hydrogels was performed to characterize the relationships between the network structure and gel properties. Small-angle neutron scattering was used to characterize the structural features of hydrogels with respect to their semidilute solution precursors. A well-defined structural length scale (correlation length) manifested as a maximum in the scattering intensity was observed for hydrogels derived from high molecular mass PEGDMs and/or high oligomer mass fractions. Hydrogels derived from lower molecular mass PEGDMs and/or low oligomer mass fractions exhibited multiple correlation lengths suggesting the formation of inhomogeneous gel structures. The shear moduli, determined from uniaxial compression measurement, showed that the gel structures correlate well with the gel mechanical properties.
Citation
Macromolecular Symposia
Volume
227

Keywords

gel structure, hydrogel, MALDI-TOF MS, mechanical properties, neutron scattering, Poly(ethylene glycol), SANS

Citation

Lin-Gibson, S. , Bencherif, S. , Antonucci, J. and JonesRL, H. (2005), Synthesis and Characterization of Poly(ethylene glycol) Dimethacrylate Hydrogels, Macromolecular Symposia, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852461 (Accessed June 16, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created December 31, 2004, Updated October 12, 2021