Krishnan, S.
, Ward, R.
, Hexemer, A.
, Sohn, K.
, Lee, K.
, Angert, E.
, Fischer, D.
, Kramer, E.
and Ober, C.
(2006),
Surfaces of Fluorinated Pyridinium Block-Copolymers with Enhanced Antibacterial Activity, Langmuir
(Accessed January 19, 2025)
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Surfaces of Fluorinated Pyridinium Block-Copolymers with Enhanced Antibacterial Activity
Published
Author(s)
Sitaraman Krishnan, R J. Ward, A Hexemer, K E. Sohn, K L. Lee, E R. Angert, , E J. Kramer, Christopher K. Ober
Abstract
Polystyrene-block-poly(4-vinylpyridine) copolymers were quaternized with 1-bromohexane and 6-perfluorooctyl-1-bromohexane. Surfaces prepared from these polymers were characterized by contact angle measurements, near-edge X-ray absorption fine structure (NEXAFS) spectroscopy and X-ray photoelectron spectroscopy (XPS). The fluorinated pyridinium surfaces showed enhanced antibacterial activity compared to their non-fluorinated counterparts. Even a polymer with a relatively low molecular weight pyridinium block showed high antimicrobial activity. The bactericidal effect was found to be related to the molecular composition and organization in the top 2-3 nm of the surface, and increased with increasing hydrophilicity and pyridinium concentration of the surface.Citation
Langmuir
Volume
22
Pub Type
Journals
Keywords
antibacterial polymers, bactericidal surfaces, fluorinated block polymers, NEXAFS, polymers, pyridinium, XPS
Citation
Issues
If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.
Created January 18, 2006, Updated October 12, 2021