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Strong and Macroporous Calcium Phosphate Cement: Effects of Porosity and Fiber Reinforcement on Mechanical Properties



Laurence C. Chow


Because of its excellent osteoconductivity and bone-replacement capability, self-setting calcium phosphate cement (CPC) has been used in a number of clincal procedures. For more rapid resorption and concomitant osseointegration, methods were desired to build macropores into CPC; however, this decreased its mechanical properties. The aims of this study, therefore, were to use fibers to strengthen macroporous CPC, and to investigate the effects of the pore volume fraction on its mechanical properties. Water-soluble mannitol crystals were incorporated into CPC paste; the set CPC was then immersed in water to dissolve mannitol, producing macropores. Mannitol/(mannitol + CPC powder) mass fractions of: 0,, 10, 20, 30, and 40 % were used. An aramid fiber volume fraction of 6 % was incorporated into the CPC-mannitol specimens, which were set in 3 mm x 4 mm x 4 mm molds and then fractured in three-point flexure to measure the strength, work of fracture, and modulus. The dissolution of mannitol created well-formed macropores, with CPC at 40% mannitol having a total porosity of a 70.8% volume fraction. Increasing the mannitol content significantly decreased the properties of CPC without fibers (analysis of variance; p
Journal of Biomedical Materials Research
No. 3


calcium phosphate cement, fiber reinforcement mechanisms, fracture resistance, hydroxyapatite, macropores, strength


Chow, L. (2001), Strong and Macroporous Calcium Phosphate Cement: Effects of Porosity and Fiber Reinforcement on Mechanical Properties, Journal of Biomedical Materials Research (Accessed June 23, 2024)


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Created December 1, 2001, Updated February 19, 2017