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Standardization of I-124 by three liquid scintillation-based methods

Published

Author(s)

Denis E. Bergeron, Leticia S. Pibida, Brian E. Zimmerman, Jeffrey T. Cessna, Ryan P. Fitzgerald

Abstract

A solution of 124I was standardized for activity by 4πβ(LS)-γ(NaI) live-timed anticoincidence (LTAC) counting, with confirmatory measurements by triple-to-double coincidence ratio (TDCR) and CIEMAT-NIST efficiency tracing (CNET) liquid scintillation counting. The LTAC-based standard was shown to be in agreement (within k = 1 uncertainties) with previous measurements at NIST and elsewhere. Calibration settings for radionuclide calibrators were determined and a discrepancy with literature values, partially due to a calibration methodology dependent upon an erroneous setting for 18F, was identified and explained.
Citation
Applied Radiation and Isotopes
Volume
154

Keywords

Iodine-124, liquid scintillation counting, Monte Carlo, dose calibrator, positron emission tomography, quantitative imaging, Fluorine-18

Citation

Bergeron, D. , Pibida, L. , Zimmerman, B. , Cessna, J. and Fitzgerald, R. (2019), Standardization of I-124 by three liquid scintillation-based methods, Applied Radiation and Isotopes, [online], https://doi.org/10.1016/j.apradiso.2019.108849 (Accessed April 15, 2021)
Created August 9, 2019, Updated March 12, 2020