Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Standard Reference Materials for Food Analysis



Melissa M. Phillips, Katherine E. Sharpless, Stephen A. Wise


Well-characterized reference materials with assigned concentrations of nutrients are needed as matrix-matched controls for analytical measurements to assist food manufacturers in quality control and facilitate compliance with nutritional labeling laws. The National Institute of Standards and Technology (NIST) has developed numerous authentic food-matrix Standard Reference Materials (SRMs) in direct response to passage of legislation such as the Infant Formula Act (IFA) of 1980 and the Nutrition Labeling and Education Act (NLEA) of 1990. At the request of the food industry, these materials have been selected to populate a nine-sectored food composition triangle developed by AOAC International. These materials are intended for use in the validation of analytical methods for determination of nutrients such as proximates, fatty acids, vitamins, and elements in food products
Analytical and Bioanalytical Chemistry


Phillips, M. , Sharpless, K. and Wise, S. (2013), Standard Reference Materials for Food Analysis, Analytical and Bioanalytical Chemistry, [online], (Accessed February 29, 2024)
Created March 21, 2013, Updated January 27, 2020