Skip to main content

NOTICE: Due to a lapse in annual appropriations, most of this website is not being updated. Learn more.

Form submissions will still be accepted but will not receive responses at this time. Sections of this site for programs using non-appropriated funds (such as NVLAP) or those that are excepted from the shutdown (such as CHIPS and NVD) will continue to be updated.

U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Standard Operation Procedures (SOPs) for the Palla VM-KT Vibrating Cryomill: Production of Fresh Frozen Standard Reference and Control Materials (SRMs/CMs) at the NIST Reference Material Production Facility

Published

Author(s)

Amanda J. Moors, Rebecca S. Pugh, Jody R. Evans, Jennifer M. Ness, Debra L. Ellisor, Melannie J. Bachman

Abstract

The NIST Reference Materials Production (RMP) Facility at the Hollings Marine Laboratory produces fresh, frozen powder materials which are used as Standard Reference Materials (SRMs) and Control Materials (CMs) from frozen biological, environmental, geological, or food related materials. These are analyzed by NIST researchers to provide certified/reference values for various types of analytical analyses (i.e. environmental contaminants, nutrient values, etc.). This facility consists of an ISO Class 7 clean room space and the Palla VM-KT Vibrating Cryomill required for producing fresh-frozen cryohomogenized materials. Described below are the procedures used to produce the fresh, frozen powder material for SRMs/CMs using the Palla VM-KT Vibrating Cryomill.
Citation
Special Publication (NIST SP) - 1196
Report Number
1196

Keywords

cryomill, Marine ESB, SRM, standard reference material

Citation

Moors, A. , Pugh, R. , Evans, J. , Ness, J. , Ellisor, D. and Bachman, M. (2016), Standard Operation Procedures (SOPs) for the Palla VM-KT Vibrating Cryomill: Production of Fresh Frozen Standard Reference and Control Materials (SRMs/CMs) at the NIST Reference Material Production Facility, Special Publication (NIST SP), National Institute of Standards and Technology, Gaithersburg, MD, [online], https://doi.org/10.6028/NIST.SP.1196 (Accessed October 9, 2025)

Issues

If you have any questions about this publication or are having problems accessing it, please contact [email protected].

Created August 11, 2016, Updated November 10, 2018
Was this page helpful?