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Simple device for rare cell capture from whole blood

Published

Author(s)

Jason G. Kralj, Samuel P. Forry, Matt S. Munson, Thomas P. Forbes, Chandamany Arya, Lynn Sorbara, Alessandro Tona, Sudhir Srivastava

Abstract

We have developed a system to isolate rare cells from whole blood using commercially available components and simple microfluidics that can provide biologists with the capabilities of the monolithic devices. We characterized the capture of MCF-7 cells spiked into whole human blood to demonstrate that enrichment and even enumeration studies are possible, and enabling engineers and biologists access to this technology.
Citation
Lab on A Chip

Keywords

microfluidics, rare cell capture, circulating tumor cells, whole blood assay

Citation

Kralj, J. , Forry, S. , Munson, M. , Forbes, T. , Arya, C. , Sorbara, L. , Tona, A. and Srivastava, S. (2012), Simple device for rare cell capture from whole blood, Lab on A Chip (Accessed April 21, 2024)
Created September 26, 2012, Updated February 19, 2017