Ridge, K.
(2008),
Rhodopsin Chemistry and Structure, Annual Review of Biophysics and Biomolecular Structure
(Accessed October 10, 2025)
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Rhodopsin Chemistry and Structure
Published
Author(s)
Abstract
Rhodopsin is a retinal photoreceptor protein of bipartite structure consisting of the transmembrane protein opsin and the light Sensitive chromophore 11-cis-retinal, linked to opsin via a protonated Schiff base. Studies on rhodopsin have unveiled many structural and functional features that are common to a large and pharmacologically important group of proteins from the G-protein-coupled receptor (GPCR) superfamily, of which rhodopsin is the best-studied member. In this work, the main emphasis will be on structural investigations. In particular, the high-resolution structure of bovine rhodopsin provides a template for understanding how GPCRs work and highlights its central importance to the visual process.Citation
Annual Review of Biophysics and Biomolecular Structure
Pub Type
Journals
Keywords
crystal structure, G-protein-coupled receptors, phototransduction, rhodopsin, signal transduction, transmembrane protein, vision, vitamin A
Citation
Issues
If you have any questions about this publication or are having problems accessing it, please contact [email protected].
Created October 16, 2008