A Review of the DNA Standard Reference Materials Developed by the National Institute of Standards and Technology
Barbara C. Levin, He Cheng, Margaret C. Kline, Janette W. Redman, Kristy L. Richie
The Standard Reference Materials Program at the U.S. National Institute of Standards and Technology (NIST) has three human DNA Standard Reference Materials (SRM 2390, SRM 2391a, and SRM 2392) currently available. Both the DNA Profiling SRM 2390 and the Polymerase Chain Reaction (PCR) - based DNA Profiling 2391a are intended for use in forensic and paternity identifications, for instructional law enforcement, or non-clinical research purposes and are not intended for clinical diagnostics. The mitochondrial DNA (mtDNA) SRM 2392 is to provide standardization and quality control when performing PCR and sequencing any segment or the entire 16,569 base pairs that comprise human mitochodrial DNA. SRM 2392 is designed for use by the forensic, medical and toxicological communities for human identification, disease diagnosis or mutation detection.
Fresenius Journal of Analytical Chemistry
DNA, forensic, human, medical diagnostics, mitochondrial DNA, PCR, RFLP, short tandem repeats, standard reference material
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, Kline, M.
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A Review of the DNA Standard Reference Materials Developed by the National Institute of Standards and Technology, Fresenius Journal of Analytical Chemistry
(Accessed June 7, 2023)