Repeatability of Magnetic Resonance Fingerprinting on T1 and T2 Estimates Assessed Using the ISMRM/NIST MRI System Phantom

Published

October 27, 2016

Author(s)

Yun Jiang, Dan Ma, Katy Keenan, Karl Stupic, Vikas Gulani, Mark Griswold

Abstract

Purpose: The purpose of this study was to evaluate accuracy and repeatability of T₁ and T₂ estimates of a MR fingerprinting (MRF) method using the ISMRM/NIST MRI system phantom. Methods: The ISMRM/NIST system phantom contains multiple compartments with standardized T₁, T₂, and proton density values. Conventional inversion-recovery spin echo and spin echo methods were used to characterize the T₁ and T₂ values in the phantom. The phantom was scanned using the MRF-FISP method over 34 consecutive days. The mean T₁ and T₂ values were compared with the values from the spin echo methods. The repeatability was characterized as the coefficient of variation of the measurements over 34 days. Results:T₁ and T₂ values from MRF-FISP over 34 days showed a strong linear correlation with the measurements from the spin echo methods (R²=0.999 for T₁; R²=0.996 for T₂). The MRF estimates over the wide ranges of T₁ and T₂ values have less than 5% variation, except for the shortest T₂ relaxation times where the method still maintains less than 8% variation. Conclusion: MRF measurements of T₁ and T₂ are highly repeatable over time and across wide ranges of T₁ and T₂ values.

Citation

Magnetic Resonance in Medicine

Issue

78

Pub Type

Journals

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Keywords

MR Fingerprinting, quantitative imaging, relaxation time, repeatability, NIST system phantom

Citation

Jiang, Y. , Ma, D. , Keenan, K. , Stupic, K. , Gulani, V. and Griswold, M. (2016), Repeatability of Magnetic Resonance Fingerprinting on T₁ and T₂ Estimates Assessed Using the ISMRM/NIST MRI System Phantom, Magnetic Resonance in Medicine, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=920978 (Accessed April 25, 2024)