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Remineralization Effect of a Low-Concentration Fluoride Rinse in an Intraoral Model



Laurence C. Chow, Shozo Takagi, Stanislav A. Frukhtbeyn, B A. Sieck, Edward E. Parry, N S. Liao, Gary E. Schumacher, Milenko Markovic


A previous study showed that a sodium hexafluorosilicate-calcium chloride-based two-solution fluoride (F) rinse containing 6 mmol/l of F was more effective than a 12 mmol/l F sodium fluoride rinse in depositing F on tooth surfaces and increasing oral F levels. The present study compared the remineralization effects of these two rinses in an intraoral de- and remineralization model. The results showed that the 6 mmol/l F two-solution rinse produced greater remineralization in increasing lesion mineral contents and reducing lesion depths. The results demonstrated that the effectiveness of an F regimen depends less on the F dose and more on the ability of the treatment to utilize F efficiently for remineralization.
Caries Research


calcium fluoride, enamel, fluoride, fluoride rinse, in vivo remineralization model, remineralization, sodiumhexafluorosilicate


Chow, L. , Takagi, S. , Frukhtbeyn, S. , Sieck, B. , Parry, E. , Liao, N. , Schumacher, G. and Markovic, M. (2002), Remineralization Effect of a Low-Concentration Fluoride Rinse in an Intraoral Model, Caries Research, [online], (Accessed May 24, 2024)


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Created April 1, 2002, Updated February 19, 2017