NOTICE: Due to a lapse in annual appropriations, most of this website is not being updated. Learn more.
Form submissions will still be accepted but will not receive responses at this time. Sections of this site for programs using non-appropriated funds (such as NVLAP) or those that are excepted from the shutdown (such as CHIPS and NVD) will continue to be updated.
An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Reduction in dentin permeability using mildly supersaturated calcium phosphate solutions
Published
Author(s)
Ai-Shuan(Maria) Cherng, Laurence C. Chow, Shozo Takagi
Abstract
Treatments that obdurate dentin tubules have been used for reducing dentin hypersensitivity. The objective of this study was to determine the effects of multiple treatments with a mildly supersaturated calcium phosphate solution on the hydraulic conductance (Lp) of partially occluded dentin discs in vitro. The treatment solution contained 6.5 mmol/L (mM) each of calcium and phosphate, 0.25 mM fluoride, 30 mM KCl, and 50 mM HEPES buffer (pH adjusted to 7.0). The mean baseline Lp (in L cm-2 min-1 H2O cm-1) was 0.108 0.041 (mean s.d.; n = 9), and after five consecutive treatments, the mean relative Lp, presented as % of baseline, were 71 11, 58 10, 46 18, 40 14, and 25 10, respectively. The Lp values of the baseline and treatment groups were significantly (p
Cherng, A.
, Chow, L.
and Takagi, S.
(2004),
Reduction in dentin permeability using mildly supersaturated calcium phosphate solutions, Archives of Oral Biology, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=851961
(Accessed October 17, 2025)