Lin-Gibson, S.
, Walls, H.
, Kennedy, S.
and Welsh, E.
(2003),
Reaction Kinetics and Gel Properties of Blocked Disocyinate Cross-Linked Chitosan Hydrogels, Carbohydrate Polymers, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852173
(Accessed March 13, 2025)
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Reaction Kinetics and Gel Properties of Blocked Disocyinate Cross-Linked Chitosan Hydrogels
Published
Author(s)
, , , E R. Welsh
Abstract
Cure kinetics and network properties of hydrogels prepared by the reaction of chitosan and a water-soluble blocked diisocyanate crosslinker have been measured using swelling experiments and rheometry. The gel time measured by two different rheological methods, the rate equivalence of the change in modulus as a function of reaction time (G'G crossover) and the critical gel via the Winter-Chambon approach, are comparable. The reaction rate increased with increased temperature following the Arrhenius behavior, from which apparent activation energies can be determined. The network moduli can be tailored by adjusting the ratio of chitosan to crosslinker or the solution concentration. This allows for the formation of processable chemically crosslinked chitosan hydrogels with controlled kinetics and mechanical properties.Citation
Carbohydrate Polymers
Pub Type
Journals
Download Paper
Keywords
chitosan, crosslink kinetics, gel modulus, hydrogels
Citation
Issues
If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.
Created May 19, 2003, Updated February 19, 2017