Quantitative, Interactive Measurement of Tissue Engineering Scaffold Structure in an Immersive Visualization Environment

Published

October 1, 2006

Author(s)

John G. Hagedorn, Joy P. Dunkers, Adele P. Peskin, John T. Kelso, Judith E. Terrill

Abstract

We describe a software system that enables the measurement and analysis of tissue engineering scaffold materials from three dimensional images that were generated with X-ray micro-computed tomography (μCT), segmented and converted to a polygonal representation. We use this system to compare an 'as designed' scaffold with a manufactured scaffold to determine differences in strut properties. Essential to this work is the use of an immersive visualization (virtual reality) system that gives the researcher the ability to interact directly with data representations in ways that are not possible with desktop systems. Structures can be inspected and measurements can be made and analyzed during the immersive session. Using these measurements, researchers can assess the fidelity of actual scaffolds to the design model and evaluate scaffold manufacturing processes. We describe future directions for more automatic measurement techniques for three dimensional images, and the role of immersive visualization in understanding and evaluating these techniques.

Citation

Biomaterials Forum

Volume

28

Issue

4

Pub Type

Journals

Keywords

High Performance Computing and Visualization Group, tissue engineering, tomography, immersive visualization

Citation

Hagedorn, J. , Dunkers, J. , Peskin, A. , Kelso, J. and Terrill, J. (2006), Quantitative, Interactive Measurement of Tissue Engineering Scaffold Structure in an Immersive Visualization Environment, Biomaterials Forum (Accessed December 15, 2024)