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Protein-Style Dynamical Transition in a Non-Biological Polymer and a Non-Aqueous Solvent

Published

Author(s)

E. Mamontov, V. K. Sharma, J. M. Borreguero, Madhu Sudan Tyagi

Abstract

Temperature-dependent onset of apparent anharmonicity in the microscopic dynamics of hydrated proteins and other biomolecules has been known as protein dynamical transition for the last quarter of a century. Using neutron scattering and molecular dynamics of one of the most common polymers, polystyrene, which was exposed to toluene vapor, mimicking the process of protein hydration from water vapor. Polystyrene with adsorbed toluene is an example of a solvent-solute system, which, unlike biopolymers, is anhydrous and lacks hydrogen bonding. Nevertheless, it exhibits the essential traits of the dynamical transition in biomolecules, such as a specific dependence of the microscopic dynamics of both solvent and host on the temperature and the amount of solvent adsorbed. We conclude that the protein dynamical transition is a manifestation of a universal solvent-solute dynamical relationship, which is not specific to either biomolecules as solute, or aqueous media as solvent, or even a particular type of interactions between solvent and solute.
Citation
Journal of Physical Chemistry B
Volume
120
Issue
2

Keywords

dynamic transition, polymer, solvent

Citation

Mamontov, E. , Sharma, V. , Borreguero, J. and Tyagi, M. (2016), Protein-Style Dynamical Transition in a Non-Biological Polymer and a Non-Aqueous Solvent, Journal of Physical Chemistry B, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=920724 (Accessed February 26, 2024)
Created April 3, 2016, Updated October 12, 2021