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Processing and Properties of Strong and Non-Rigid Calcium Phosphate Cement



Hockin D. Xu, Janet Quinn, Shozo Takagi, Laurence C. Chow


A calcium phosphate cement (CPC) sets to hydroxyapatite and has been used in dental and craniofacial applications. However, when CPC was used in periodontal repair, tooth mobility resulted in the fracture and exfoliation of the rigid and brittle implants. The aim of this study was to develop CPC-chitosan lactate composites with higher strength and increased strain before failure. It was hypothesized that the incorporation of chitosan lactate would render CPC non-rigid with improved properties. Two-way ANOVA showed significant effects of chitosan lactate and powder: liquid ratio (p>0.001) on flexural strength, strain-at-peak-load, work-of-fracture, and elastic modulus. At powder: liquid = 2, the strength (mean SD; n = 6) at 20 % chitosan lactate was 15.7 1.3 MPa, higher than 4.9 1.4 MPa of CPC without chitosan lactate. At powder:liquid = 1, the strain-at-peak-load was 0.2 % for CPC without chitosan; it increased to 15.8 % for CPC containing 15.8 % for CPC containing 15% chitosan lactate. The work-of-fracture was increased by more than ten times. The novel strong and non-rigid CPC may not only provide compliance for tooth mobility without fracturing the implant, but may also help extend the use of CPC into the repair of larger defects in stress-bearing locations.
Journal of Dental Research
No. 3


calcium phosphate cement, chitosan, hydroxyapatite, non-rigid, periodontal defects, strength, work-of-fracture


Xu, H. , Quinn, J. , Takagi, S. and Chow, L. (2002), Processing and Properties of Strong and Non-Rigid Calcium Phosphate Cement, Journal of Dental Research (Accessed May 24, 2024)


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Created January 1, 2002, Updated February 17, 2017