Preparation of Nanoparticles by Continuous-Flow Microfluidics
Andreas Jahn, Joseph E. Reiner, Wyatt N. Vreeland, Don DeVoe, Laurie E. Locascio, Michael Gaitan
We review a variety of micro- and nanoparticle formulations produced with microfluidic methods. A diverse variety of approaches to generate micro-scale and nano-scale particles have been reported. Here we emphasize the use of microfluidics, specifically microfluidic systems that operate in a continuous flow mode, thereby allowing continuous generation of desired particle formulations. The generation of semiconductor quantum dots, metal colloids, emulsions, and liposomes is considered here. To emphasize the potential benefits of the continuous-flow microfluidic methodology for nanoparticle generation, preliminary data on the size distribution of liposomes formed using the microfluidic approach is compared to the traditional bulk alcohol injection method.
, Reiner, J.
, Vreeland, W.
, DeVoe, D.
, Locascio, L.
and Gaitan, M.
Preparation of Nanoparticles by Continuous-Flow Microfluidics, Journal of Nanoparticle Research, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=32842
(Accessed September 25, 2023)