Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

One-Laser Interferometric Broadband Coherent Anti-Stokes Raman Scattering



T W. Kee, Hongxia (Jessica) Zhao, Marcus T. Cicerone


We introduce an interferometric technique for eliminating the nonresonant background of broadband coherent anti-Stokes Raman scattering (CARS) microscopy. CARS microscopy has been used for imaging a number of biological samples and processes, but the studies are mostly limited to detecting lipids in biological systems by probing the C-H stretch. Nonresonant background and incoherent noise sources can easily overwhelm less intense signals from other molecular vibrations. In this study, we demonstrate a one-laser broadband interferometric technique that separates the spontaneous Raman scattering-related component of the CARS signal from the nonresonant background.
Optics Express


coherent anti-Stokes Raman scattering, fibers, interferometry, microscopy, nonlinear optics, spectroscopy


Kee, T. , , H. and Cicerone, M. (2006), One-Laser Interferometric Broadband Coherent Anti-Stokes Raman Scattering, Optics Express, [online], (Accessed June 21, 2024)


If you have any questions about this publication or are having problems accessing it, please contact

Created March 30, 2006, Updated February 19, 2017