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One-Laser Interferometric Broadband Coherent Anti-Stokes Raman Scattering

Published

Author(s)

T W. Kee, Hongxia (Jessica) Zhao, Marcus T. Cicerone

Abstract

We introduce an interferometric technique for eliminating the nonresonant background of broadband coherent anti-Stokes Raman scattering (CARS) microscopy. CARS microscopy has been used for imaging a number of biological samples and processes, but the studies are mostly limited to detecting lipids in biological systems by probing the C-H stretch. Nonresonant background and incoherent noise sources can easily overwhelm less intense signals from other molecular vibrations. In this study, we demonstrate a one-laser broadband interferometric technique that separates the spontaneous Raman scattering-related component of the CARS signal from the nonresonant background.
Citation
Optics Express
Volume
14
Issue
8

Keywords

coherent anti-Stokes Raman scattering, fibers, interferometry, microscopy, nonlinear optics, spectroscopy

Citation

Kee, T. , , H. and Cicerone, M. (2006), One-Laser Interferometric Broadband Coherent Anti-Stokes Raman Scattering, Optics Express, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852851 (Accessed October 13, 2025)

Issues

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Created March 30, 2006, Updated February 19, 2017
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