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T W. Kee, Hongxia (Jessica) Zhao, Marcus T. Cicerone
Abstract
We introduce an interferometric technique for eliminating the nonresonant background of broadband coherent anti-Stokes Raman scattering (CARS) microscopy. CARS microscopy has been used for imaging a number of biological samples and processes, but the studies are mostly limited to detecting lipids in biological systems by probing the C-H stretch. Nonresonant background and incoherent noise sources can easily overwhelm less intense signals from other molecular vibrations. In this study, we demonstrate a one-laser broadband interferometric technique that separates the spontaneous Raman scattering-related component of the CARS signal from the nonresonant background.
Kee, T.
, , H.
and Cicerone, M.
(2006),
One-Laser Interferometric Broadband Coherent Anti-Stokes Raman Scattering, Optics Express, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852851
(Accessed October 13, 2025)