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In the last two decades the interactions of organic molecules with different inorganic minerals have been the focus of considerable biomineralization and biomaterial research. The elucidation of the role of macromolecules, e.g. collagen, proteins, and polymers, in the nucleation, aggregation, and phase transformation of calcium phosphate biominerals principally calcium hydroxyapatite (HA), Ca10(PO4)6(OH)2, octacalcium phosphate (OCP), Ca8(HPO4)2(PO4)4 5H2O, and dicalcium phosphate dihydrate (DCPD), CaHPO4 2H2O in normal and pathological mineralization has been of special interest. Less attention has been given to the incorporation of small organic molecules into the inorganic structures, which is another relevant aspect of physiological organic/inorganic interactions.