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NIST Traveling Tunable Laser Projector (TTLP) for UV-Blue Disinfection Dose Determinations



Thomas C. Larason, Steven Grantham, Clarence Zarobila, Yuqin Zong, C Cameron Miller, Michael Schuit, Brian Holland, Stewart Wood, Melissa Krause


As COVID-19 was overtaking the world in the spring of 2020, the National Institute of Standards and Technology began collaborating with the National Biodefense Analysis and Countermeasures Center to study the inactivation of SARS-CoV-2 to different UV and blue light wavelengths. This paper describes a 1 kHz pulsed laser and projection system used to study the doses required to inactive SARS-CoV-2 over the wavelength range of 222 nm–488 nm. This paper builds on NIST's previous work for water pathogen inactivation using UV laser irradiation. The design of the laser and projection system and its performance in the Biosafety Level 3 (BSL-3) laboratory are given. The SARS-CoV-2 inactivation results published elsewhere (Publication by Schuit, M.A., et al., expected 2022), demonstrate that a tunable laser projection system is an invaluable tool for this research.
Applied Optics


Action Spectra, SARS-CoV-2 Inactivation, Ultraviolet Light, Blue Light, Tunable Laser


Larason, T. , Grantham, S. , Zarobila, C. , Zong, Y. , Miller, C. , Schuit, M. , Holland, B. , Wood, S. and Krause, M. (2022), NIST Traveling Tunable Laser Projector (TTLP) for UV-Blue Disinfection Dose Determinations, Applied Optics, [online],, (Accessed May 19, 2024)


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Created June 21, 2022, Updated November 29, 2022