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A New Synthetic Method for Controlled Polymerization of HPMA Using a Microfluidic System



Tao Wu, Ying Mei, J Cabral, Chang Xu, Kathryn L. Beers


Atom transfer radical polymerizations (ATRP) were performed in a microfluidic channel, fabricated in a solvent resistant polymer matrix. Compared to conventional batch polymerization, microfluidic platforms offer a unique opportunity to handle small samples in high volumes with both time and space control. In our experiments, we show continuous polymerization of hydroxyl propyl methacrylate (HPMA) in the microfluidic channel. We are able to control molecular weight by regulating reaction times using different constant pumping rate. Alternately, we can control input of reagent ratios to control molecular weight, composition and architecture of the polymer output. This method is one piece of a larger platform being designed to formulate polymeric materials using microfluidic technology.
Proceedings Title
Sigma Xi Postdoctoral Poster Presentations, 2004
Conference Dates
February 19-20, 2004
Conference Title
Sigma Xi Web Page


controlled polymerization, HPMA, microfluidic system, synthetic method


Wu, T. , Mei, Y. , Cabral, J. , Xu, C. and Beers, K. (2004), A New Synthetic Method for Controlled Polymerization of HPMA Using a Microfluidic System, Sigma Xi Postdoctoral Poster Presentations, 2004, [online], (Accessed March 4, 2024)
Created February 1, 2004, Updated February 19, 2017