Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Neutron Scattering in the Biological Sciences: Progress and Prospects

Published

Author(s)

Rana Ashkar, Hassina Z. Bilheux, Heliosa Bordallo, Robert Briber, David J. E. Callaway, Xiaolin Cheng, Xiang-Qiang Chu, Joseph E. Curtis, Mark Dadmun, Paul Fenimore, David Fushman, Frank Gabel, Kushol Gupta, Frederick Herberle, Frank Heinrich, Liang Hong, John Katsaras, Zvi Kelman, Eugenia Kharlampieva, Gerald R. Kneller, Andrey Kovalevsky, Susan T. Krueger, Paul Langan, Raquel Lieberman, Yun Liu, Mathias Losche, Edward Lyman, Yimin NMN Mao, John Marino, Carla Mattos, Flora Meilleur, Peter Moody, Jonathan D. Nickels, William B. O'Dell, Hugh O'Neill, Ursula Perez-Salas, Judith Peters, Loukas Petridis, Alexei P. Sokolov, Robert Sutherland, Norman Wagner, Michael NMN Weinrich, Kevin Weiss, Troy Wymore, Yang Zhang, Jeremy C. Smith

Abstract

The scattering of neutrons can be used to provide information on the structure and dynamics of biological systems on multiple scales of length and time. Pursuant to an NSF-funded workshop in February 2018, we review recent developments in this field as well as future prospects than can be expected given recent advances in sources, instrumentation and computational power and methods. Crystallography, solution scattering, dynamics, membranes, labelling and imaging are examined. For the extraction of maximum information the incorporation of judicious specific deuterium labelling, the integration of several types of experiment, and interpretation using high-performance computer simulation models are found to often be particularly powerful.
Citation
Acta Crystallographica Section D-Biological Crystallography
Volume
D74
Issue
12

Keywords

neutron scattering, biological systems, structural biology, biological dynamics

Citation

Ashkar, R. , Bilheux, H. , Bordallo, H. , Briber, R. , Callaway, D. , Cheng, X. , Chu, X. , Curtis, J. , Dadmun, M. , Fenimore, P. , Fushman, D. , Gabel, F. , Gupta, K. , Herberle, F. , Heinrich, F. , Hong, L. , Katsaras, J. , Kelman, Z. , Kharlampieva, E. , Kneller, G. , Kovalevsky, A. , Krueger, S. , Langan, P. , Lieberman, R. , Liu, Y. , Losche, M. , Lyman, E. , Mao, Y. , Marino, J. , Mattos, C. , Meilleur, F. , Moody, P. , Nickels, J. , O'Dell, W. , O'Neill, H. , Perez-Salas, U. , Peters, J. , Petridis, L. , Sokolov, A. , Sutherland, R. , Wagner, N. , Weinrich, M. , Weiss, K. , Wymore, T. , Zhang, Y. and Smith, J. (2018), Neutron Scattering in the Biological Sciences: Progress and Prospects, Acta Crystallographica Section D-Biological Crystallography, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=926669 (Accessed May 19, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created November 30, 2018, Updated October 12, 2021