Microfluidic Platform for the Generation of Organic-Phase Microreactors

Published

April 1, 2005

Author(s)

Zuzanna T. Cygan, J Cabral, Kathryn L. Beers, Eric J. Amis

Abstract

Rapid prototyping photolithography of a thiolene based resin was used to fabricate microfluidic devices stable to aliphatic and aromatic organic solvents. The swelling of the thiolene resin in various organic solvents was quantified and the solvent resistance properties of these microfluidic devices are described. Discrete droplets of hexanes and toluene of uniform size were generated in a water matrix containing SDS surfactant (SDS = sodium dodecylsulfate). Variation of water and organic flow rate in the fluidic channels was used to control droplet size and separation, and droplet composition could be controlled by varying flow rates of two joined organic streams. Organic phase synthetic reactions within the droplets were demonstrated with the bromination of alkenes inside of droplets of benzene.

Citation

Langmuir

Volume

21

Issue

No. 8

Pub Type

Journals

Keywords

droplet formation, microfluidics, microreactors, photolithography, solvent swelling

Citation

Cygan, Z. , Cabral, J. , Beers, K. and Amis, E. (2005), Microfluidic Platform for the Generation of Organic-Phase Microreactors, Langmuir (Accessed October 3, 2023)