U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PUBLICATIONS

Micellar Affinity Gradient Focusing

Published

Author(s)

K M. Balss, P B. Howell, David J. Ross

Abstract

This report describes a novel method for the concentration and separation of neutral and/or hydrophobic analytes based on a combination of the analytes partitioning into a micellar phase and their electrophoretic mobility. This method of simultaneous separation and concentration of species, which we call micellar affinity gradient focusing (MAGF) is effectively a combination of micellar electrokinetic chromatography (MEKC) and temperature gradient focusing (TGF). MEKC separates neutral species based on their partitioning into an ionic micelle whereas TGF separates analytes based on differences in electrophoretic velocity; in MAGF these two characteristics together determine the point at which an analyte focuses in the separation channel.
Citation
Journal of the American Chemical Society
Volume
126
Issue
7
Pub Type
Journals

Keywords

MEKC, neutral analytes, separations, TGF

Citation

Balss, K. , Howell, P. and Ross, D. (2004), Micellar Affinity Gradient Focusing, Journal of the American Chemical Society (Accessed July 1, 2025)

Issues

If you have any questions about this publication or are having problems accessing it, please contact [email protected].

Created February 25, 2004, Updated February 17, 2017
Was this page helpful?