Methodology for Obtaining and Using Toxic Potency Data for Fire Hazard Analysis
Vyto Babrauskas, Richard Gann, Barbara C. Levin, M Paabo, Richard H. Harris Jr., Richard Peacock, S Yusa
A comprehensive methodology has been developed for obtaining and using smoke toxicity data for fire hazard analysis. This description of the methodology comprises (1) determination that the post-flashover fire is the proper focus of smoke inhalation deaths; criteria for a useful bench-scale toxic potency (LC,,) measurement method; (2) a method which meets these criteria, especially validation against real-scale fires; (3) a computational procedure for correcting the results from the bench-scale test for the CO levels observed in real-scale post-flashover fires; (4) procedures for reducing the usage of animals and broadening the applicability of data by interpreting gas measurement data using the N-Gas Model; and (5) a procedure for identifying whether a product produces smoke within the ordinary range of toxic potency for post-flashover fires.
, Gann, R.
, Levin, B.
, Paabo, M.
, Harris Jr., R.
, Peacock, R.
and Yusa, S.
Methodology for Obtaining and Using Toxic Potency Data for Fire Hazard Analysis, Fire Safety Journal, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=913064
(Accessed January 26, 2022)