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Methodological Challenges in Including Green Tea Dietary Supplements to Analytically Verified Databases.



Kate Rimmer, Leila Saldanha, Johanna Dwyer, Karen Andrews, Regan Bailey, Joseph Betz, Vicki Burt, Rebecca Costello, Nancy Emenaker, Jaime Gahche, J. Harnly, Constance Hardy, Pamela R. Pehrsson


Dietary supplement databases are needed to calculate total dietary intakes from foods and supplements. Analytically verified databases are necessary for commonly consumed products as estimates of intakes are used in guiding public policy decisions. The Dietary Supplement Ingredient Database (DSID) is a federally-funded database that currently contains analytically derived information on dietary ingredients with labeling daily values in adult, child and prenatal over-the-counter (OTC) multi-vitamin and mineral (MVM) supplements. However, other ingredients that do not have daily values such as botanicals are of interest and being considered for inclusion in DSID. The process for adding these dietary ingredients are described. Prioritization criteria were public exposure intake and sales, the availability of validated analytical methods and reference materials, and the reason for analysis. The 41 non-daily value dietary ingredients prioritized included acai, aloe, B-carotene, black cohosh, cascara, chondroitin, cocoa/flavonols, CoQ10, cranberry, creatine, echinacea, elderberry, flaxseed, garlic, garlic, ginkgo biloba, ginseng, glucosamine, goldenseal, goldenseal, green tea catechins, guarana, lutein, lutein, lycopene, milk thistle, MSM, natural herbal sources of vitamin C, phytosterols, prebiotics, probiotics, psyllium, red leaf clover, S-adenosylmethionine (SAMe), saw palmetto, soy products, stevia, synephrine/bitter orange, turmeric, valerian, and yohimbe. Of these, green tea was selected as the candidate botanical supplement based on critical factors necessary for the inclusion of products reported in the DSID. The paper includes a detailed discussion of these critical factors, which is the availability of appropriate reference materials, analytical methods, and qualified laboratories for analyzing the active constituents in green tea dietary supplement products.
Journal of Food Science


database, nutrition, green tea, reference materials


Rimmer, K. , Saldanha, L. , Dwyer, J. , Andrews, K. , Bailey, R. , Betz, J. , Burt, V. , Costello, R. , Emenaker, N. , Gahche, J. , Harnly, J. , Hardy, C. and Pehrsson, P. (2015), Methodological Challenges in Including Green Tea Dietary Supplements to Analytically Verified Databases., Journal of Food Science (Accessed May 26, 2024)


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Created April 1, 2015, Updated January 18, 2023