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A medical device-grade T1 and ECV phantom for global T1 mapping quality assurance - The T1 Mapping and ECV Standardization in cardiovascular magnetic resonance (T1MES) program

Published

Author(s)

Gabriella Captur, Peter Gatehouse, Katy Keenan, Friso Heslinga, Ruediger Bruehl, Marcel Prothmann, Martin J. Graves, Richard J. Eames, Camilla Torlasco, Giulia Benedetti, Jacqueline Donovan, Bernd Ittermann, Redha Boubertakh, Andrew Bathgate, Celine Royet, Wenjie Pang, Reza Nezafat, Michael Salerno, Peter Kellman, James C. Moon

Abstract

Background: T1 mapping and extracellular volume (ECV) have the potential to guide patient care and serve as surrogate end-points in clinical trials, but measurements differ between cardiovascular magnetic resonance (CMR) scanners and pulse sequences. To help deliver T1 mapping to global clinical care, we developed a phantom-based quality assurance (QA) system for verification of measurement stability over time at individual sites, with further aims of generalization of results across sites, vendor systems, software versions and imaging sequences. We thus created T1MES: The T1 Mapping and ECV Standardization Program.
Citation
Journal of Cardiovascular Magnetic Resonance

Citation

Captur, G. , Gatehouse, P. , Keenan, K. , Heslinga, F. , Bruehl, R. , Prothmann, M. , Graves, M. , Eames, R. , Torlasco, C. , Benedetti, G. , Donovan, J. , Ittermann, B. , Boubertakh, R. , Bathgate, A. , Royet, C. , Pang, W. , Nezafat, R. , Salerno, M. , Kellman, P. and Moon, J. (2016), A medical device-grade T1 and ECV phantom for global T1 mapping quality assurance - The T<sub>1</sub> Mapping and ECV Standardization in cardiovascular magnetic resonance (T1MES) program, Journal of Cardiovascular Magnetic Resonance, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=920632 (Accessed October 8, 2025)

Issues

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Created September 21, 2016, Updated October 12, 2021
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