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HIV Protease Structural Database

Published

Author(s)

Veerasamy Ravichandran, J Vondrasek, G L. Gilliland, Talapady N. Bhat, A Wlodawer

Abstract

The HIV Protease Database (HIVdb) is a web-based archive for HIV protease structural information. HIVdb contains experimentally determined three-dimensional structures of human immunodeficiency virus type 1 (HIV-1), human immunodeficiency virus type 2 (HIV-2), and simian immunodeficiency virus (SIV) proteases and their complexes with inhibitors or products of substrate cleavage. This resource provides macromolecular structural data on HIV and related proteases and tools to analyze this data to scientists engaged in basic research, in the development of drugs and in the development of therapies in the fight against AIDS. The structural holdings of the HIVdb are from two sources, the Protein Data Bank (PDB) and from academic, government and industrial laboratories that have not deposited the coordinates in the PDB. The HIVdb can be accessed via the web at http://xpdb.nist.gov/chemblast/pdb.pl .
Proceedings Title
IEEE Computer Society Bioinformatics Conference | | | IEEE
Conference Dates
August 1, 2002
Conference Title
IEEE Computer Society Bioinformatics Conference

Keywords

crystal, HIV Protease Database, protein, structural biology database, structure-based drug design
Created August 1, 2002, Updated February 17, 2017