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Estimating Common Parameters in Heterogeneous Random Effects Models

Published

Author(s)

Andrew L. Rukhin

Abstract

A question of fundamental importance for meta-analysis of heterogeneous data studies is how to form a best consensus estimator of common parameters, and what uncertainty to attach to the estimate. This issue is addressed for a class of unbalanced linear designs which include classical growth curve models. The obtained solution is similar to the DerSimonian and Laird (1986) popular method for a simple meta-analysis model. By using almost unbiased variance estimators, an estimator of the covariance matrix of this procedure is derived. These methods are illustrated by two examples and are compared via simulation.
Citation
Technometrics

Keywords

almost unbiased estimator, DerSimonian-Laird estimator, estimating equations, Graybill-Deal estimator, maximum likelihood, meta-analysis, random effects model, variance components.

Citation

Rukhin, A. (2011), Estimating Common Parameters in Heterogeneous Random Effects Models, Technometrics, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=904659 (Accessed October 9, 2025)

Issues

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Created April 13, 2011, Updated February 19, 2017
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