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Effects of Polymerization Initiator Complexation in Methacrylated Beta-Cyclodextrin Formulations



L A. Hussain, Sabine H. Dickens, Rafael L. Bowen


Objectives: Methacrylated beta-cyclodextrin (MCD) is a candidate dental monomer that can complex molecules within its hydrophobic cavity. This study determined the effects of complexation of polymerization initiators such as camphorquinone (CQ) and ethyl 4-dimethylaminobenzoate (4E) with MCD on the flexural strength (FS) and degree of conversion (DC) of resulting dental composite formulations. Methods: Complexation of CQ and 4E with MCD was studied by thin layer chromatography. A mass fraction of 44 % 2-hydroxyethyl methacrylate or triethyleneglycol dimethacrylate was mixed separately with a mass fraction of 56 % MCD to produce a workable formulation. The mixture was activated with varied amounts of CQ and 4E. One part by mass of the activated resin formulation was mixed with 3 parts by mass of glass filler. Specimens for FS were prepared by filling molds with composites and cured for 2 min.The cured specimens were immersed in 37 oC water for 24 h and FS was measured with an Instron machine at a crosshead speed of 0.5 mm/min. DC in MCD-based resin formulations was measured with a differential photocalorimeter under nitrogen. Results: MCD appears to form inclusion complexes with CQ and 4E. As a result, FS and DC of MCD-based composites vary significantly as a function of the concentration of polymerization initiators used in the formulations. Significance: Complexation of polymerization initiators with MCD can influence the FS and DC in MCD-based dental formulations and should be taken into consideration when evaluating MCD as a dental monomer.
Dental Materials Congress


cyclodextrin methacrylates, dental composites, polymerization initiator complexation


Hussain, L. , Dickens, S. and Bowen, R. (2004), Effects of Polymerization Initiator Complexation in Methacrylated Beta-Cyclodextrin Formulations, Dental Materials Congress, [online], (Accessed April 24, 2024)
Created July 1, 2004, Updated February 17, 2017