U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PUBLICATIONS

Effect of Solvent Quality on the Molecualr Dimensions of PAMAM Dendrimers

Published

Author(s)

A Topp, Barry J. Bauer, D A. Tomalia, Eric J. Amis

Abstract

The average dimensions of poly (amido amine) (PAMAM) dendrimers of generation numbers G5 and G8 are measured by small angle neutron scattering as a function of solvents of different quality, of the composition of mixtures of a good solvent and a non-solvent, and of temperature. The radius of gyration of the G8 dendrimer, Rg, decreases for the series of solvents D(CD2)mOD (with m = 0, 1, 2, 4) by approximately 10 % with decreasing solvent quality. The amount of swelling of PAMAM dendrimers, as reflected by Rg, is not influenced by the composition of mixtures of methyl alcohol/acetone in the full range of solubility of the dendrimers. In the temperature range - 10 degrees {Celsius} g value. The average segment densities are calculated for G5 and G8 under various solvent conditions, with the dendrimers containing volume fractions of solvent between 0.43 and 0.60.
Citation
Macromolecules
Volume
32
Issue
No. 21
Pub Type
Journals

Keywords

dendrimer, PAMAM, radius of gyration, SANS, solvent

Citation

Topp, A. , Bauer, B. , Tomalia, D. and Amis, E. (1999), Effect of Solvent Quality on the Molecualr Dimensions of PAMAM Dendrimers, Macromolecules (Accessed September 14, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created October 1, 1999, Updated February 17, 2017