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Effect of Polymeric Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells

Published

Author(s)

Girish Kumar, Marian F. Young, Carl Simon Jr.

Abstract

Structural properties of polymeric scaffolds for bone tissue engineering play key role in directing osteogenesis. These properties depend on the chemical nature and the fabrication process of biomaterial. There are many protocols for fabricating scaffolds for bone tissue engineering applications which afford control over scaffold topology. In addition, much work has demonstrated that cell differentiation is sensitive to topology at sizes ranging from nano- to micro- to macroscale1. Thus, we have investigated the effect of different scaffold topologies on differentiation of human bone marrow stromal cells (hBMSCs).
Conference Dates
December 5-7, 2010
Conference Location
Orlando, FL, US
Conference Title
TERMIS

Keywords

tissue engineering, polymer scaffold, stem cell, cell differentiation, bone, osteogenesis

Citation

Kumar, G. , Young, M. and Simon Jr., C. (2010), Effect of Polymeric Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells, TERMIS, Orlando, FL, US, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=906518 (Accessed March 4, 2024)
Created December 16, 2010, Updated October 12, 2021