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Digital Phantoms Generated by Spectral and Spatial Light Modulators

Published

Author(s)

Bonghwan Chon, Fuyuki Tokumasu, Ji Y. Lee, David W. Allen, Joseph P. Rice, Jeeseong Hwang

Abstract

A hyperspectral image projector (HIP) based on liquid crystal on silicon (LCoS) spatial light modulators (SLMs) is explained and demonstrated to generate 3D spectral data cubes. The HIP- constructed data cubes are 3D images of the spatial distribution of spectrally resolved abundances of intracellular light-absorbing oxy-hemoglobin molecules in single erythrocytes. Spectrally and spatially resolved image data indistinguishable from the real scene may be used as standard data cubes, so-called digital phantoms, to calibrate image sensors and validate image analysis algorithms for their measurement quality, performance consistency, and inter-laboratory comparisons for quantitative biomedical imaging applications.
Citation
Journal of Biomedical Optics
Volume
20
Issue
12

Keywords

hyperspectral imaging, optical imaging standard, digital phantom, molecular imaging, single cell imaging, scatter imaging, spatial light modulator
Created October 21, 2015, Updated November 10, 2018