Digital Phantoms Generated by Spectral and Spatial Light Modulators
Bonghwan Chon, Fuyuki Tokumasu, Ji Y. Lee, David W. Allen, Joseph P. Rice, Jeeseong Hwang
A hyperspectral image projector (HIP) based on liquid crystal on silicon (LCoS) spatial light modulators (SLMs) is explained and demonstrated to generate 3D spectral data cubes. The HIP- constructed data cubes are 3D images of the spatial distribution of spectrally resolved abundances of intracellular light-absorbing oxy-hemoglobin molecules in single erythrocytes. Spectrally and spatially resolved image data indistinguishable from the real scene may be used as standard data cubes, so-called digital phantoms, to calibrate image sensors and validate image analysis algorithms for their measurement quality, performance consistency, and inter-laboratory comparisons for quantitative biomedical imaging applications.