Digital Phantoms Generated by Spectral and Spatial Light Modulators

Published

October 21, 2015

Author(s)

Bonghwan Chon, Fuyuki Tokumasu, Ji Y. Lee, David W. Allen, Joseph P. Rice, Jeeseong Hwang

Abstract

A hyperspectral image projector (HIP) based on liquid crystal on silicon (LCoS) spatial light modulators (SLMs) is explained and demonstrated to generate 3D spectral data cubes. The HIP- constructed data cubes are 3D images of the spatial distribution of spectrally resolved abundances of intracellular light-absorbing oxy-hemoglobin molecules in single erythrocytes. Spectrally and spatially resolved image data indistinguishable from the real scene may be used as standard data cubes, so-called digital phantoms, to calibrate image sensors and validate image analysis algorithms for their measurement quality, performance consistency, and inter-laboratory comparisons for quantitative biomedical imaging applications.

Citation

Journal of Biomedical Optics

Volume

20

Issue

12

Pub Type

Journals

Download Paper

https://doi.org/10.1117/1.JBO.20.12.121309

Keywords

hyperspectral imaging, optical imaging standard, digital phantom, molecular imaging, single cell imaging, scatter imaging, spatial light modulator

Citation

Chon, B. , Tokumasu, F. , Lee, J. , Allen, D. , Rice, J. and Hwang, J. (2015), Digital Phantoms Generated by Spectral and Spatial Light Modulators, Journal of Biomedical Optics, [online], https://doi.org/10.1117/1.JBO.20.12.121309 (Accessed March 13, 2025)