Skip to main content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Determination of Ethanol Concentration in Alcoholic Beverages by Direct Analysis in Real Time Mass Spectrometry (DART-MS)

Published

Author(s)

Edward R. Sisco, Elizabeth L. Robinson

Abstract

Determination of the ethanol concentration in beverages remains a common request to forensic laboratories. While traditionally completed using headspace gas chromatography (HS-GC), this process involves lengthy run times and the need for specialized headspace sampling equipment for the GC system. The work presented here highlights a potential alternative to HS-GC analysis, using direct analysis in real time mass spectrometry (DART-MS). By incorporating a simple T-junction to the orifice of the mass spectrometer, analysis of the headspace of a beverage can be completed, resulting in measurement of the ethanol concentration in a matter of seconds with greater than 99 % accuracy. This work presents the development of a method for ethanol quantitation as well as results from the analysis of both ethanol reference material standards and in-house created ethanol-containing solutions to evaluate the precision and accuracy of the technique. Analysis of ethanolic beverages via DART-MS has been shown to be a rapid and reliable alternative to traditional analysis by HS-GC.
Citation
Forensic Chemistry
Volume
18

Keywords

Alcohol, DART-MS, Ethanol, Quantitation
Created January 17, 2020, Updated February 13, 2020