Data Standards for Proteomics: Mitochondrial Two-Dimensional Polyacrylamide Gel Electrophoresis Data as a Model System
Veerasamy Ravichandran, G B. Vasquez, S Srivastava, M Verma, E Petricoin, Joshua Lubell, Ram D. Sriram, Peter E. Barker, G L. Gilliland
The advent of human proteomics as a major discipline has led to a reexamination of the need for consensus and a nationally sanctioned set of proteomics technology standards. Such standards for databases and data reporting may be applied to Two-Dimensional Polyacrylamide Gel Electrophoresis technology as a pilot project for assessing global and national needs in proteomics, and various roles for the National Institute of Standards and Technology (NIST) and other similar standards and measurement organizations. The experience harmonizing heterogeneous data included in the New Protein Data Bank (PDB) provides a paradigm for technology where significant heterogeneity in technical detail and data storage has evolved. Here we propose an approach toward standardizing 2D-PAGE data in support of a globally relevant proteomics consensus.
data repository, data standards, proteomics, two-dimensional electrophoresis
, Vasquez, G.
, Srivastava, S.
, Verma, M.
, Petricoin, E.
, Lubell, J.
, Sriram, R.
, Barker, P.
and Gilliland, G.
Data Standards for Proteomics: Mitochondrial Two-Dimensional Polyacrylamide Gel Electrophoresis Data as a Model System, Mitochondrion
(Accessed December 5, 2023)