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Controlling the Fluoride Dose in a Patient with Compromised Salivary Function: A Case Report

Published

Author(s)

F Eichmiller, Naomi Eidelman, Clifton M. Carey

Abstract

ckground: High concentration topical fluorides are commonly used to prevent caries in patients with compromised salivary function due to radiation and chemotherapy. Case Description: A cancer patient using tray-applied topical fluoride gel complained fo gastric symptoms, difficulty in swallowing, leg muscle sorness, and knee joint sorness. CT scan revealed thickening of the esophagus walls. Upper endoscopy found abnormal motility. The motility test indicated high amplitude peristalsis and hypertensive LES, and urine testing indicated high levels of systemic fluoride. The patient's fluoride regimen was altered until urinary fluoride levels returned to normal levels and symptoms resolved within a short period of time. Clinical Implications: Clinicans prescribing home-applied high concentration fluorides need to be cognizant of the symptoms of fluoride toxicity, to monitor patient, and to adjust the dose or mode of application and control the total ingested dose.
Citation
Journal of the American Dental Association
Volume
136

Keywords

caries, dose fluoride, toxicity, treatment xerostomia

Citation

Eichmiller, F. , Eidelman, N. and Carey, C. (2005), Controlling the Fluoride Dose in a Patient with Compromised Salivary Function: A Case Report, Journal of the American Dental Association, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852223 (Accessed May 26, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created January 1, 2005, Updated February 17, 2017