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A Collaborative Enterprise for Multi-Stakeholder Participation in the Advancement of Quantitative Imaging

Published

Author(s)

Lisa R. Karam, Andrew Buckler, Hugo J. Aerts, Bernard Bendriem, Claus Bendtsen, Ronald Boellaard, John M. Boone, Linda Bresolin, Deborah Burstein, William Bushnell, Patricia E. Cole, James J. Conklin, Gary S. Dorfman, Pamela S. Douglas, N. R. Dunnick, Willy Eidsaunet, Cathy Elsinger, Richard F. Frank, Constantine Gatsonis, Maryellen L. Giger, David Gustafson, Sandeep N. Gupta, Otto S. Hoekstra, Edward F. Jackson, Gary J. Kelloff, Paul E. Kinahan, Geoffrey McLennan, Colin G. Miller, P D. Mozley, Keith E. Muller, Kevin O'Donnell, Rick Patt, Divid Raunig, Mark Rosen, Heren Rupani, Lawrence H. Schwartz, Barry A. Siegel, A. G. Sorensen, Richard L. Wahl, John C. Waterton, Walter Wolf, Gudrun Zahlmann, Brian E. Zimmerman, Daniel C. Sullivan

Abstract

Medical imaging has seen significant and rapid technical advances over the last decade, including image acquisition devices, processing and analysis software, and agents to enhance specificity. Traditionally medical imaging has defined anatomy, but increasingly it also provides biochemical and physiological information based on both static and dynamic modalities. Therefore medical imaging is important not only for detecting disease, but for characterizing and assessing change of disease with time or therapy. This evolution demands that newer imaging technologies be appropriately developed, assessed, regulated, and reimbursed in an efficient and methodical process, thereby benefitting the biomedical research community, therapeutics developers, health care delivery enterprises, and ultimately individual patients. Because of these rapid technical advances, research to determine the utility of quantitative imaging in either clinical research or clinical practice has not had time to mature. To help address this, we have formed a collaborative program - the Quantitative Imaging Biomarker Alliance (QIBA). QIBA enables cooperation among the stakeholders to directly address the validation, standardization, regulation and reimbursement of quantitative medical imaging. It draws from the very successful precedent set by the Integrating the Healthcare Enterprise effort, but is adapted to the needs of imaging science. Strategic guidance supporting the development, qualification and deployment of quantitative imaging biomarkers will lead to improved standardization of imaging tests, proof of imaging test performance and greater use of imaging to predict tissue biologic behavior and monitoring therapy response. These in turn confer value to corporate stakeholders, providing incentives to bring new and innovative products to market.
Citation
Radiology

Keywords

imaging assay, imaging biomarker, imaging standardization, quantitative imaging

Citation

Karam, L. , Buckler, A. , Aerts, H. , Bendriem, B. , Bendtsen, C. , Boellaard, R. , Boone, J. , Bresolin, L. , Burstein, D. , Bushnell, W. , Cole, P. , Conklin, J. , Dorfman, G. , Douglas, P. , Dunnick, N. , Eidsaunet, W. , Elsinger, C. , Frank, R. , Gatsonis, C. , Giger, M. , Gustafson, D. , Gupta, S. , Hoekstra, O. , Jackson, E. , Kelloff, G. , Kinahan, P. , McLennan, G. , Miller, C. , Mozley, P. , Muller, K. , O'Donnell, K. , Patt, R. , Raunig, D. , Rosen, M. , Rupani, H. , Schwartz, L. , Siegel, B. , Sorensen, A. , Wahl, R. , Waterton, J. , Wolf, W. , Zahlmann, G. , Zimmerman, B. and Sullivan, D. (2011), A Collaborative Enterprise for Multi-Stakeholder Participation in the Advancement of Quantitative Imaging, Radiology, [online], https://doi.org/10.1148/radiol.10100799, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=905697 (Accessed February 11, 2025)

Issues

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Created March 1, 2011, Updated January 14, 2025