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Biotech SRMs Designed for the Rapidly Evolving Forensic DNA and Human Identity Testing Communities

Published

Author(s)

Margaret C. Kline, David L. Duewer, John M. Butler

Abstract

As advances in biotechnology have been applied to human identification, the National Institute of Standards and Technology (NIST) has provided Standard Reference Material (SRM ) to aid the forensic community to assure the quality of their measurements. SRM 2390 DNA Profiling Standard for Restriction Fragment Length Polymorphism (RFLP) analysis was issued in 1992. SRM 2391 PCR-based DNA Profiling Standard for Variable Number of Tandem Repeat (VNTR), Short Tandem Repeat (STR) and Single Nucleotide Polymorphism (SNP) loci was released in 1995, with renewals issued in 1998 and 2003. SRM 2392 Mitochondrial DNA Sequencing Standard (human) was released in late 1999, it is now being updated. SRM 2395 Human Y-chromosome DNA Profiling Standard will be issued in mid-2003. SRM 2372 Human DNA Quantitation Standard is in development.
Proceedings Title
NCSL International 2003 Workshop and Symposium Conference Proceedings | | The Spectrum of Metrology: From the State of the Art to the Everyday |
Conference Dates
August 17-20, 2003
Conference Title
National Conference of Standards Laboratories International

Keywords

DNA typing, restriction fragment length polymorphism, short tandem repeat, single nucleotide polymorphisms, Standard Reference Materials

Citation

Kline, M. , Duewer, D. and Butler, J. (2003), Biotech SRMs Designed for the Rapidly Evolving Forensic DNA and Human Identity Testing Communities, NCSL International 2003 Workshop and Symposium Conference Proceedings | | The Spectrum of Metrology: From the State of the Art to the Everyday | (Accessed April 21, 2024)
Created August 1, 2003, Updated February 17, 2017