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Archaeal DNA replication

Published

Author(s)

Zvi Kelman, Lori M. Kelman

Abstract

DNA replication is an essential process for all life forms. While the process is fundamentally conserved in the three domains of life, bioinformatics, biochemical, structural and genetic studies have demonstrated that the process and the proteins involved in archaeal replication are much closer to those in eukarya than to bacteria, with some archaeal-specific features. Similar to bacteria and eukarya, the archaeal replication system is not monolithic and there are some differences in the replication process between different species. In this review the current knowledge of the mechanisms governing DNA replication in archaea is summarized. The general features of the replication process as well as some of the differences are discussed.
Citation
Annual Review of Genetics
Volume
48

Keywords

archaea, initiation of DNA replication, protein-DNA interactions, protein-protein interactions, regulation of DNA replication, protein structure

Citation

Kelman, Z. and Kelman, L. (2014), Archaeal DNA replication, Annual Review of Genetics, [online], https://doi.org/10.1146/annurev-genet-120213-09214 (Accessed April 18, 2024)
Created November 3, 2014, Updated November 10, 2018