Large-scale room fire testing has evolved from simple fire performance measurements such as intensity and duration of 'room fires' to sophisticated measurements to understand the properties which cause the fire. This paper provides a overview of typical calculations, based upon published research results, that are used at the Center for Fire Research and elsewhere for the analysis of a large-scale room fire test. Analysis of large-scale fire test data requires the development of a series of algorithms that combine individual measurements to produce the desired physical quantity. A set of algorithms for the analysis of fire test data based upon published research results is described. Included are fire-specific calculations such as smoke and gas analysis, layer temperature and interface position, mass loss and flows, and rate of heat release. Examples of the application of the calculations are provided.