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Spotlight: Screening for Kidney Disease With Accurate Measurements

A woman wearing purple gloves adjusts tubing inside a scientific device.
Credit: M. DeLorme

If you have a fear of needles, getting a urine test is a pain-free way for doctors to screen for kidney disease or any signs of kidney damage. Clinicians measure albumin, a protein abundant in blood, in urine samples to assess kidney function. 

But how do clinicians and scientists make sure those measurements are accurate? 

Cue NIST and bioanalytical chemist Ashley Beasley Green (shown here with a liquid chromatography-mass spectrometer). Ashley leads our urine albumin standardization program, and she’s working to develop a standard reference material for albumin in human urine, which can improve the accuracy of measurements for diagnosing and managing kidney disease.

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Released April 15, 2021, Updated October 18, 2022