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Bioscience & Health Programs & Projects

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Biocompatibility of Photoluminescent Silicon Nanoparticles
Last Updated Date: 10/01/2012

Photoluminescent silicon nanoparticles have a bright and stable fluorescence and are promising candidates for use in bio-imaging, cell staining … more

Standards for Immuno-Histochemical Imaging: A Biomarker Protein Expression Chip
Last Updated Date: 10/01/2012

Immunohistochemistry (IHC) is used to visualize antigens in tissue sections by specific antigen-antibody interactions, an advantage over … more

Development of SRMs for Serum Proteomics
Last Updated Date: 10/01/2012

Serum proteomics, the detection and measurement of as many proteins in a serum sample as possible, could be an important element of personalized … more

Fundamental Interaction Mechanisms of Engineered Nanomaterials with DNA
Last Updated Date: 10/01/2012

We utilized isotope-dilution liquid chromatography/mass spectrometry (LC/MS) to determine the levels of the oxidatively damaged DNA bases, … more

Ontologies and Interoperability in Evolutionary Comparative Analysis
Last Updated Date: 10/01/2012

Many computer-based inferences in contemporary biology are comparative and would benefit from the rigorous and flexible approach of evolutionary … more

Structural Databases
Last Updated Date: 10/01/2012

We are witnessing the emergence of a web based "data rich" era on chemical and biological compounds. In order to make significant advances in this … more

Controlling Microfluidic Cell Culture Environments
Last Updated Date: 10/01/2012

NIST has taken advantage of recent technological advances to develop polymer microfluidic cell culture systems that provide a level of control … more

Decontamination of Biological Threats in Water Supplies
Last Updated Date: 10/01/2012

The availability of safe pure drinking water in the United States is taken for granted. The presence of dangerous microorganisms, viruses and … more

Relative Intensity Correction Standards for Fluorescence and Raman Spectroscopy
Last Updated Date: 10/01/2012

Luminescence measurements have become the methods of choice for new clinical and biochemical analyses due to their high selectivity and … more

Quantification of Cells with Specific Phenotypic Characteristics
Last Updated Date: 10/01/2012

Flow cytometers are versatile instruments that have been successfully used to enumerate cell subsets in infectious diseases (e.g., HIV) and to … more

Thermodynamics of Enzyme-catalyzed Reactions
Last Updated Date: 10/01/2012

To develop the thermodynamic data and methodology required for effective bioprocess engineering.

Nanoparticle Accumulation and Distribution in Organisms
Last Updated Date: 10/01/2012

Given the substantial differences between nanoparticles (NPs) and typical organic and inorganic environmental contaminants, new experimental … more

Genotoxicity of Nanoparticles
Last Updated Date: 10/01/2012

As a result of their novel properties, nanoparticles are expected to be produced and incorporated into consumer products at exponentially … more

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