Biological physics

News and Updates

NIST Researchers Develop a Breakthrough COVID-19 Detection Technology

October 2, 2023

“Only connect” is the most famous line in the British novelist E. M. Forster’s writings. Forster was urging the readers of his book Howard’s End to make

white matter mimic in the bottom half of the artificial cranium

Lessons from an Experimental Brain Phantom

July 12, 2023

Researchers at the National Institute of Standards and Technology (NIST) and colleagues have developed a novel, anatomically accurate reference model of the

New NIST Licensing Opportunity Teems with Potential Applications

July 5, 2023

Max Planck, one of the Twentieth Century’s most eminent physicists, observed, "An experiment is a question that science poses to Nature, and a measurement is

Projects and Programs

viral vector illustration with RNA seen within the capsid

Gene Delivery Particle Analysis with High-Throughput Light Scattering Microscopy

Ongoing

Measurement Techniques for Membranes and Membrane Proteins

Ongoing

Synthetic cell membrane constructs allow the simplification and complete control of a more complicated cellular system, as well as the incorporation of selected

State-resolved Spectroscopy of Biomolecules

Ongoing

Sensitive and fully state resolved spectroscopic methods in the terahertz (THz) and ultraviolet (UV) regions are being developed to investigate the structure

X-ray computed tomography (CT)

Ongoing

Current work in x-ray computed tomography centers on diffraction effects in micro CT and computed tomography of integrated circuit interconnects.

Publications

Quantifying a light-induced energetic change in bacteriorhodopsin by force spectroscopy

February 7, 2024

Author(s)

David Jacobson, Thomas T. Perkins

Influence of fluorescence lifetime selections and conformational flexibiiliy on brightness of FusionRed variants

February 5, 2024

Author(s)

Srijit Mukherjee, Nancy Douglas, Ralph Jimenez

Narrowing Signal Distribution by Adamantane Derivatization for Amino Acid Identification Using α-Hemolysin Nanopore

January 24, 2024

Author(s)

Xiaojun Wei, Dumei Ma, Junlin Ou, Ge Song, Jiawei Guo, Joseph Robertson, Yi Wang, Qian Wang, Chang Liu

Nanopores have demonstrated remarkable sensitivity as biosensors, enabling the sequencing of DNA and RNA at the single-molecule level. The rapid progress in

High-resolution infrared spectroscopy of jet cooled cyclobutyl in the α-CH stretch region: Large-amplitude puckering dynamics in a 4-membered ring radical

January 5, 2024

Author(s)

Ya-Chu Chan, David Nesbitt

Software

NIST's Integrated Colony Enumerator (NICE)

January 4, 2021

Enumeration of bacterial colonies on an agar plate is simple in concept, but automated colony counting is difficult due to variations in colony color, size

Tools and Instruments

Beamline 10: Quantitative Hyperspectral Infrared Microscopy

The new beamline 10, currently under construction, is intended for applications that make use of the super-thermal brightness from SURF in the near- to mid