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Search Publications by: Mark Lowenthal (Fed)

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Displaying 26 - 32 of 32

Mass Spectrometry Characterization for Chemoenzymatic Glycoprotein Synthesis

July 1, 2011
Author(s)
John E. Schiel, Mark S. Lowenthal, Karen W. Phinney
Glycoproteins exist as heterogeneous mixtures of glycoforms due to glycosylation at multiple sites with various glycans. The glycosylation pattern has significant implications for clinical diagnostics and biopharmaceutical development because it affects

Stable isotope-labeling of DNA repair proteins, and their purification and characterization

July 1, 2011
Author(s)
M Miral Dizdar, Pawel Jaruga, Prasad T. Reddy, Bryant C. Nelson, Mark S. Lowenthal
Reduced DNA repair capacity is associated with increased risk for a variety of disease processes including carcinogenesis. Thus, DNA repair proteins have the potential to be used as important predictive, prognostic and therapeutic biomarkers in cancer and

Comparison of Orthogonal Mass Spectrometry Platforms for the Determination of Amino Acid Concentrations in Human Plasma Certifying NIST Standard Reference Material 1950

August 16, 2010
Author(s)
Mark S. Lowenthal, Karen W. Phinney, Elizabeth A. McGaw
Absolute concentrations of amino acids in a human plasma pool were determined independently using four quantification methods. Orthogonal separation schemes (LC, GC, or GCxGC) and detection systems (triple quadrupole or time-of-flight mass spectrometers)