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You searched on: Topic Area: Life Sciences Research

Displaying records 11 to 20 of 148 records.
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11. Machine Learning Analysis for Identification of Cell Shape Metrics Associated with Stem Cell Differentiation in Nanofiber Scaffolds
Topic: Life Sciences Research
Published: 4/19/2014
Authors: Desu Chen, Sumona Sarkar, Stephen J Florczyk, Subhadip Bodhak, Carl George Simon Jr., Joy P Dunkers, Julian Candia, Wolfgang Losert
Abstract: Cell shape has been demonstrated to be closely related to cell function and may be an important predictor of cell fate. Many metrics are available to describe cell shape, however the relationship of these metrics to cell fate are not well understood ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914971

12. Roles of Nanofiber Structure and Chemistry in Directing Stem Cell Morphology, Differentiation and Gene Expression
Topic: Life Sciences Research
Published: 4/19/2014
Authors: Sumona Sarkar, Bryan A. Baker, Desu Chen, Wolfgang Losert, Carl George Simon Jr., Joy P Dunkers
Abstract: Nanofiber technology has emerged as a promising tool to recapitulate the native extracellular matrix (ECM) environment for tissue engineering and regenerative medicine strategies. Cell-material interactions in the nanofiber system are largely de ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914988

13. Why human genome sequencing platforms differ: Integrating sequencing datasets to understand biases and form consensus variant calls
Topic: Life Sciences Research
Published: 2/16/2014
Authors: Justin M Zook, Brad Chapman, Winston Hide, Marc L Salit
Abstract: Hundreds of thousands of differences exist between human whole genome variant calls from different sequencing platforms and variant calling pipelines, but the reasons for these differences are poorly understood. Well-characterized whole genome Refer ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912658

14. Airbrushed Nanofiber Scaffolds Support Bone Marrow Stromal Cell Differentiation
Topic: Life Sciences Research
Published: 11/1/2013
Authors: Carl George Simon Jr., Wojtek J Tutak, Sumona Sarkar, Tanya M. Farooque, Jyotsnendu J. Giri, Dongbo Wang, Sheng Lin-Gibson, Joachim Kohn, Durgadas Bolikal
Abstract: Nanofiber scaffolds are effective for tissue engineering since they emulate the fibrous nanostructure of native extracellular matrix (ECM). Although electrospinning has been the most common approach for fabricating nanofiber scaffolds, airbrushi ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912293

15. Some Journal Metrics for Forensic Science International: Genetics
Topic: Life Sciences Research
Published: 10/2/2013
Author: John M Butler
Abstract: Forensic Science International: Genetics, which is the official journal of the International Society for Forensic Genetics, has grown in readership and impact factor since its introduction in 2007. This article reviews some metrics of the 32 issu ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914636

16. Evaluation of Vitamin D Standardization Program protocols for standardizing serum 25-hydroxyvitamin D data: a case study of the program's potential for national nutrition and health surveys
Topic: Life Sciences Research
Published: 6/3/2013
Authors: Karen W Phinney, Kevin Cashman, Mairead Kiely, Michael Kinsella, Ramon Durazo-Arvizu, Lu Tian, Yue Zhang, Alice Lucey, Albert Flynn, Michael Gibney, Mary Frances Picciano, Christopher T. Sempos
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915282

17. Effect of Surface Chemistry on Stem Cell Response in 2-D vs. 3-D Cell Culture Niches
Topic: Life Sciences Research
Published: 4/19/2013
Authors: Sumona Sarkar, Carl George Simon Jr., Roberta I Lock, Joy P Dunkers
Abstract: To develop tissue engineered devices for regenerative medicine strategies, key scaffold properties for directing stem cell response must be identified. As focus shifts from 2-D to 3-D culture systems in an attempt to better recapitulate the na ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912888

18. Next-generation Sequencing: Guidance for the Translation from Research to Clinical Applications
Topic: Life Sciences Research
Published: 11/8/2012
Authors: Justin M Zook, Amy Gargis, Lisa Kalman, Ira Lubin
Abstract: We would like to draw your readers‰ attention to the Next-generation Sequencing: Standardization of Clinical Testing (Nex-StoCT) guidelines, which represent an initial step toward ensuring that the results derived from next-generation sequencing (N ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=910560

19. GENERATING CELL CO-CULTURES BY RAPID CELL ADHESION ON OPPOSITE SIDES OF POLYESTER MEMBRANES
Topic: Life Sciences Research
Published: 10/28/2012
Authors: Conni Hanke, Petra S. Dittrich, Darwin R Reyes-Hernandez
Abstract: A cell co-culture was generated on opposite sides of a permeable polyester membrane (PET) membrane by combining dielectrophoretic (DEP) and electrostatic forces to hold cells against gravity in a multilayer microfluidic device (Figure 1). HepG2 cell ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911771

20. Characterization of In Vitro Transcription Amplification Linearity and Variability in the Low Copy Number Regime using ERCC Spike Ins
Topic: Life Sciences Research
Published: 10/20/2012
Authors: Jason G Kralj, Marc L Salit
Abstract: Background Characterization of whole transcriptomes from small RNA samples (less than 1 ng total RNA) has been a major challenge. Typically, samples are extracted and purified, amplified by in vitro transcription (IVT), and then subjected to genome- ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=909936



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