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Topic Area: Drugs/Pharmaceuticals
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Displaying records 31 to 40 of 48 records.
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31. Probing the Nature of Ibuprofen Confined in Mesoporous Media by Neutron Vibrational Spectroscopy and First-Principles Calculations
Topic: Drugs/Pharmaceuticals
Published: 5/15/2012
Author: Ken Kangyi Qian
Abstract: {B}Purpose{/B}: In this paper, the nature of ibuprofen incorporated into both mesoporous silicon dioxide and magnesium aluminometasilicate by sublimation and adsorption was investigated using neutron vibrational spectroscopy. {B}Methods{/B}: Crystall ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=910370

32. Protein Particles: What We Know and What We Don‰t Know
Topic: Drugs/Pharmaceuticals
Published: 6/26/2012
Authors: Dean C Ripple, Mariana Dimitrova
Abstract: All therapeutic protein products contain particles formed by the aggregation of protein monomers. There is a growing interest in the understanding of particles in biopharmaceutical products, which has been fostered on the one hand by significant ad ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=910991

33. Quantification of Drugs of Abuse in Municipal Wastewater via SPE and Direct Injection Liquid Chromatography Mass Spectrometry
Topic: Drugs/Pharmaceuticals
Published: 9/24/2010
Authors: Michele M Schantz, Katrice A Lippa, Kevin Bisceglia, A. Lynn Roberts
Abstract: We present an isotopic dilution direct injection reverse phase liquid chromatography-tandem mass spectrometry (RPLC/MS/MS) method for the simultaneous determination of 23 drugs of abuse, drug metabolites, and human use markers in municipal wastewater ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904046

34. Quantifying Dithiothreitol Displacement of Functional Ligands from Gold Nanoparticles
Topic: Drugs/Pharmaceuticals
Published: 10/27/2012
Authors: De-Hao D. Tsai, Frank W DelRio, Sherrie R. Elzey, Suvajyoti S. Guha, Michael Russel Zachariah, Vincent A Hackley, Melanie P Shelton
Abstract: Dithiothreitol (DTT)-based displacement is widely utilized for separating ligands from their gold nanoparticle (AuNP) conjugates, a critical step for differentiating and quantifying surface-bound functional ligands and therefore the effective surface ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911354

35. Quantitation of HER2 and Telomerase Biomarkers in Solid Tumors with IgY Antibodies and Nanocrystal Detection
Topic: Drugs/Pharmaceuticals
Published: 5/15/2008
Authors: Yan Xiao, X Gao, G Gannot, M Emmert-Buck, S Srivastava, Paul D Wagner, Michael D. Amos, Peter E. Dr. Barker
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901234

36. Quantitative Analysis of Dendron-Conjugated Cisplatin-Complexed Gold Nanoparticles Using Scanning Particle Mobility Mass Spectrometry
Topic: Drugs/Pharmaceuticals
Published: 5/8/2013
Authors: De-Hao D. Tsai, Tae Joon Cho, Sherrie R. Elzey, Julien C. Gigault, Vincent A Hackley
Abstract: We report a high-resolution and traceable method to quantify the drug loading on nanoparticle-based cancer therapeutics, and demonstrate this method using a model cisplatin functionalized dendron-gold nanoparticle (AuNP) conjugate. Electrospray diffe ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912782

37. Recent Advances in Electrochemical Glyco-biosensing
Topic: Drugs/Pharmaceuticals
Published: 4/8/2011
Authors: Rebecca A Zangmeister, Germarie Sanchez-Pomales
Abstract: Biosensors based on electrochemical transduction mechanisms have recently made advances into the field of glycan analysis. These glyco-biosensor assays offer simple, rapid, sensitive and economical approaches to the measurement need for rapid glycan ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908197

38. Semantic Web for the Life Sciences Hype, Why, How and Use Case for AIDS Inhibitors
Topic: Drugs/Pharmaceuticals
Published: 7/1/2007
Authors: Talapady N Bhat, John Barkley
Abstract: There is considerable interest in the Semantic Web as a solution to the growing information technology needs of biological data and drug discovery. However, the progress towards this vision has been very limited. One reason for this slow progress is ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830549

39. Solid State Chemistry of Proteins: II. The Correlation of Storage Stability of Freeze-Dried Human Growth Hormone (hGH) With Structure and Dynamics in the Glassy Solid
Topic: Drugs/Pharmaceuticals
Published: 12/1/2008
Authors: Michael Pikal, Daniel Rigsbee, Michael L Roy, Dawn Galreath, Karl J Kovach, Bingquan S. Wang, John F Carpenter, Marcus T Cicerone
Abstract: This research presents storage stability of human growth hormone, hGH, in a variety of lyophilized formulations, including systems of varying sugar:hGH weight ratios for both sucrose and trehalose. Stability was assessed at multiple time points durin ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=852769

40. Standards for the Optical Detection of Protein Particulates
Topic: Drugs/Pharmaceuticals
Published: 1/23/2012
Authors: Dean C Ripple, Michael J Carrier, Joshua R. Wayment
Abstract: Particulates in protein therapeutics, composed of agglomerated protein monomers, may cause an immunogenic response in patients. Consequently, industry and the FDA desire more accurate methods for counting and characterizing particulates. Unlike lik ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908731



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